Department of Zoology

Dr. Vidya G. (HoD)

Assistant Professor

Date of Joining

: 01-10-2019

Area of interest

: CANCER BIOLOGY

No of years of experience

: 2 years

Course Institution Year
B.Sc. Zoology Little Flower College 2008
M.Sc. Applied Zoology Calicut University 2010
PhD Institute of Bioinformatics and Applied Biotechnology 2018
PostDoctoral Fellow Indian Institute of Science 2019
Designation Institution Period
Project Assistant Indian Institute of Science 2011 to 2014
PhD Institute of Bioinformatics and Applied Biotechnology 2014-2018
PostDoctoral Fellow Indian Institute of Science 2018-2019
Assistant Professor St.Joseph's College(Autonomous), Irinjalakuda 2019 to till date
Name of award/fellowship Awarded by Year
CSIR-JRF CSIR 2011
CSIR-SRF CSIR 2015
Title Sanctioned By Amount Period
Screening for antiproliferative activity of unexplored plants belonging to Sapotaceae family using human normal & cancer cell lines KSE ltd, Irinjalakuda 18 Lakhs 20-Dec-20 to 20-Dec-23
Investigation of anticancer potential of Anisochilus carnosus and Hypericum japonicum extracts and evaluation of their underlying mechanism St. Joseph's College, Irinjalakuda 40,000 25-May-21 to 25-May-23
Title Year Indexed in Citation
Vidya Gopalakrishnan, Urbi Roy, Shikha Srivastava, Khyati M. Kariya, Shivangi Sharma, Saniya M. Javedakar, Bibha Choudhary, Sathees C. Raghavan. Delineating the mechanism of fragility at BCL^ breakpoint region associated with translocations in diffuse large B cell lymphoma. Cellular and Molecular Life science, 2024, 81.21. 2024 Scopus
Nitu Kumari1, Kohal Das1, Shivangi Sharma1, Sumedha Dahal1, Sagar Sanjiv Desai, Urbi Roy1, Anju Sharma1, Meghana Manjunath, Vidya Gopalakrishnan1, S. T. Retheesh, Saniya M. Javadekar, Bibha Choudhary and Sathees C. Raghavan.Evaluation of potential role of R loop and G quadruplex DNA in the fragility of c MYC during chromosomal translocation associated with Burkitt's lymphoma, 2023, J Biol Chem.;299(12):105431. 2023 Scopus
Vidya Gopalakrishnan and Sathees C. Raghavan, Sequence and Structural Basis for Chromosomal Fragility During Translocations in Cancer, Future Oncology 8:1121-34, 2012. 2012 Scopus, Web of Science
Mridula Nambiar, Mrinal Srivastava, Vidya Gopalakrishnan, Sritha K. Sankaran and Sathees C. Raghavan, G-quadruplex Structures Formed at the HOX11 Breakpoint Region contribute to its fragility during t(10;14) Translocation in T-cell Leukemia, Mol. Cell. Biol. 33: 4266-81, 2013. 2013 Scopus, Web of Science
Sujeet Kumar, Mahesh Hegde, Vidya Gopalakrishnan, Renuka VK, Ramareddy SA, De Clercq E, Schols D, Gudibabande Narasimhamurthy AK, Sathees C. Raghavan, Subhas S.Karki, 2-(4-Chlorobenzyl)-6-arylimidazo[2,1-b][1,3,4]thiadiazoles: Synthesis, cytotoxic activity and mechanism of action. Eur. J. Med. Chem. 84:687-97. doi: 10.1016/j.ejmech.2014.07.054. PMID: 25064346, 2014. 2014 Scopus, Web of Science
Sujeet Kumar, Vidya Gopalakrishnan, Mahesh Hegde, Vivek Rana, Sharad S. Dhepe, Sureshbabu A. Ramareddy, Alberto Leoni, Alessandra Locatelli, Rita Morigi, Mirella Rambaldi, Mrinal Srivastava, Sathees C. Raghavan, Subhas S. Karki, Synthesis and Antiproliferative Activity of Imidazo[2,1-b][1,3,4]thiadiazole Derivatives. Bioorg. Med. Chem. Let. 24:4682-8, 2014. 2014 Scopus, Web of Science
Kishore K. Chiruvella, Nishana M, Vidya Gopalakrishnan, Somasagara R. Ranganatha, Tadi Satish Kumar, Santhini Elango, Sathees C. Raghavan and Bibha Choudhary, Plant-derived Tetranortriterpenoid, Methyl Angolensate Activates Apoptosis and Prevents Ehrlich Ascites Carcinoma Induced Tumorigenesis in Mice, British J. Med Med. Res. 12:1-10, 2016. 2016 Scopus, Web of Science
) Elizabeth Thomas, Vidya Gopalakrishnan, Bibha Choudhary and Sathees C. Raghavan, Extract of Vernonia condensata, Inhibits Tumor Progression and Improves Survival of Tumor-allograft Bearing Mouse, Sci. Rep. 6: 23255, 2016. 2016 Scopus, Web of Science
Supriya V. Vartak, Mahesh Hegde, Divyaanka Iyer, Snehal Gaikwad, Mrinal Srivastava, Vidya Gopalakrishnan, Subhas S. Karki, Bibha Choudhary, Pritha Ray and Sathees C. Raghavan, A Novel Inhibitor of BCL2 Induces Tumor Regression By Activating Intrinisic Pathway of Apoptosis, Biochemical Pharmacology. 122:10-22, 2016. 2016 Scopus, Web of Science
Elizabeth Thomas, Vidya Gopalakrishnan, Mahesh Hegde, Sujeet Kumar, Subhas S. Karki, Bibha Choudhary and Sathees C. Raghavan, A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells, Sci. Rep. 6:34653, 2016. 2016 Scopus, Web of Science
Shikha Srivastava, Sumedha Dahal, Sharanya Naidu, Deepika Anand, Vidya Gopalakrishnan, Rajendran Kooloth Valappil and Sathees C Raghavan, DNA Double-strand Break Repair in Penaeus monodon is Predominantly Dependent on Homologous Recombination, DNA Res. 24(2):117-128, 2017. 2017 Scopus, Web of Science
Mahesh Hegde, Vartak SV, Chandagirikoppal V. Kavitha, Ananda Hanumappa, Doddakunche S. Prasanna, Vidya Gopalakrishnan, Bibha Choudhary, Kanchugarakoppal S. Rangappa and Sathees C. Raghavan, A Benzothiozole Derivative (5g) Induces DNA Damage and Potent G2/M Arrest in Cancer Cells, Sci. Rep. 7(1):2533, 2017. 2017 Scopus, Web of Science
Supriya V Vartak, Swarup HA, Vidya Gopalakrishnan, Gopinatha VK, Ropars V, Mridula Nambiar, John F, Kothanahally SKS, Rupa Kumari, Nitu Kumari, Ujjaiyinee Ray, Dinesh D, Monica Pandey, Ananda H, Karki SS, Mrinal Srivastava, Charbonnier JB, Bibha Choudhary, Kempegowda Mantelingu, Sathees C Raghavan, Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner, 285(21):3959-3976, 2018 2018 Scopus, Web of Science
Vidya Gopalakrishnan, Sumedha Dahal, Gudapureddy Radha, Shivangi Sharma, Sathees C. Raghavan, Bibha Choudhary, Characterisation of DNA Double-strand Break Repair Pathways in Diffuse Large B cell Lymphoma , Molecular Carcinogenesis, 58(2):219-233, 2019. 2019 Scopus, Web of Science
Vidya Gopalakrishnan, Gudapureddy Radha, Sathees C. Raghavan, Bibha Choudhary Inhibitor of Nonhomologous End Joining can Inhibit Proliferation of Diffuse Large B?Cell Lymphoma Cells and Potentiate the Effect of Ionization Radiation, J. Radiat. Cancer. Res. 9:93-101, 2018 2018 Scopus, Web of Science
Nitu Kumari, Supriya V. Vartak, Sumedha Dahal, Susmita Kumari*, Sagar S. Desai**, Vidya Gopalakrishnan**, Sumedha Dahal, Bibha Choudhary and Sathees C. Raghavan Differential Radiosensitivity of the Human Genome is Linked to G-quadruplex Structures and could be Modulated in a Cell Cycle Dependent Manner, iScience, 21:288-307, 2019. 2019 Scopus, Web of Science
Ujjaiyinee Ray, Shivangi Sharma, Kapoor I, Susmita Kumari, Vidya Gopalakrishnan, Supriya V. Vartak, Nitu Kumari, Umesh Varshney, Sathees C. Raghavan. G4 DNA present at human telomeric DNA contributes toward reduced sensitivity to ?-radiation induced oxidative damage, but not bulky adduct formation. International Journal Radiation Biology 2021;97(9):1166-1180. doi: 10.1080/09553002.2021.1955997. Epub 2021 Aug 6. PMID: 34259614. 2021 Scopus, Web of Science
Vidya Gopalakrishnan, Shivangi Sharma, Ujjaiyinee Ray, Meghana Manjunath, Divya Lakshmanan, Supriya V. Vartak, Vindhya K. Gopinatha, Mrinal Srivastava, Mantelingu Kempegowda, Bibha Choudhary and Sathees C. Raghavan. SCR7, an inhibitor of NHEJ can sensitize tumor cells to ionization radiation. Molecular Carcinogenesis. 2021 Sep;60(9):627-643. doi: 10.1002/mc.23329. Epub 2021 Jun 30. PMID: 34192388 2021 Scopus, Web of Science
Title Funded By Collaborators Period
Webinar on Women in life science wil-2020 Department of Zoology college 2020
Webinar on ‘Ethics in Research’ Department of Zoology college 2020
Webinar on ‘DNA Origami : How does our genome fold’ Department of Zoology college 2020
Role Year
Joint Convenor in College Women's Cell committee 2021
Convenor for Value Education program 2021
Title Organized By Period
4-Week Induction/orientation programme for “Faculty in Universities/Colleges/Institutes of higher education” Ramanujan College, University of Delhi 2020
Moodle based Learning Management System Sree Neelakanta Government Sanskrit College, Pattambi 2020
R Programming St. Joseph’s College (Autonomous), Irinjalakuda 2020
Teaching and Learning in the Post Covid Era St. Joseph’s College (Autonomous), Irinjalakuda 2021
UG/ PG Paper Title
UG Physiology and Endocrinology
UG Reproductive health and Sex education
UG Biochemistry and Molecular Biology
UG Genetics and Immunology
UG Physiology and Ethology
UG Animal Diversity : Nonchordata Part-II
UG Animal Diversity : Nonchordata Part-I

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